Using a supercomputer to understand synaptic transmission
"When a cell gets excited by electrical signals, very fast synaptic vesicle fusion occurs. The neurotransmitters come out of the cell and bind to receptors on the synaptic side. That's the signal and ...
How Does the Brain Learn?
Despite their importance, the long-term dynamics of their synaptic changes have been experimentally characterized between only a few types of PCs, and shown to be diverse. As a result, there has been ...
Long-term synaptic plasticity in hippocampal interneurons
Hippocampal interneurons express at least two forms of activity-dependent long-term potentiation (LTP) at glutamatergic synapses. One form ('Hebbian' LTP) depends on N-methyl-D-aspartate (NMDA ...
Receptor trafficking and synaptic plasticity
Synaptic plasticity is the basis of information storage in the brain. Two of the most studied forms of plasticity, long-term potentiation (LTP) and long-term depression (LTD), involve both ...
Research sheds light on mechanism by which long-term anti-anxiety drug use affects the brain
ANSTO health researchers have contributed to an international study published in Nature Neuroscience that sheds light on the mechanism by which anti-anxiety drugs act on the brain which could lead to ...
Mechanisms of plasticity
Discovery of LTP. Long term potentiation was first reported in the perforant path (entorhinal cortex - dentate gyrus in the hippocampal formation). Mounted on the ...
AMPA Receptors and Synaptic Plasticity
Synaptic receptors could then be translocated out from the synapse. These two processes could combine to produce the long-lasting loss of synaptic AMPA receptors that is thought to be the molecular ...
Associative memory model with long-tail-distributed Hebbian synaptic connections
Extremely strong synapses are rare in such a weight distribution and the majority of synapses are weak. Therefore, we may term neural networks with long-tailed synaptic weight distributions “SSWD ...
Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders
elimination and long-term plasticity, whereas stable information storage and stereotyped behaviours require circuit constancy in the form of stable, enduring and homeostatic synaptic networks. How ...
“synaptic activity”的例句
Selective glutamate uptake blockers are critical tools for studying the roles of glutamate transporters in modulating synaptic activity –. Conversely, long-term depression of synaptic activity may ...
